Package: DominoEffect
Type: Package
Title: Identification and Annotation of Protein Hotspot Residues
Version: 1.30.0
Author: Marija Buljan and Peter Blattmann
Maintainer: Marija Buljan <marija.buljan.2@gmail.com>, Peter Blattmann <peter_blattmann@bluewin.ch>
Description: The functions support identification and annotation of hotspot 
    residues in proteins. These are individual amino acids that accumulate 
    mutations at a much higher rate than their surrounding regions.
License: GPL (>= 3)
Encoding: UTF-8
LazyData: true
Depends: R(>= 3.5)
Imports: biomaRt, data.table, utils, stats, Biostrings, pwalign,
        SummarizedExperiment, VariantAnnotation, AnnotationDbi,
        Seqinfo, IRanges, GenomicRanges, methods
Suggests: knitr, testthat, rmarkdown
RoxygenNote: 6.0.1
VignetteBuilder: knitr
biocViews: Software, SomaticMutation, Proteomics, SequenceMatching,
        Alignment
NeedsCompilation: no
git_url: https://git.bioconductor.org/packages/DominoEffect
git_branch: RELEASE_3_22
git_last_commit: 6694070
git_last_commit_date: 2025-10-29
Repository: Bioconductor 3.22
Date/Publication: 2025-10-29
Packaged: 2025-10-30 03:42:18 UTC; biocbuild
