Package: CytoGLMM
Type: Package
Title: Conditional Differential Analysis for Flow and Mass Cytometry
        Experiments
Version: 1.18.0
Authors@R: c(
    person("Christof", "Seiler", , "christof.seiler@maastrichtuniversity.nl", 
    role = c("aut", "cre"), 
    comment = c(ORCID = "0000-0001-8802-3642"))
    )
Description: The CytoGLMM R package implements two multiple regression 
  strategies: A bootstrapped generalized linear model (GLM) and a generalized 
  linear mixed model (GLMM). Most current data analysis tools compare 
  expressions across many computationally discovered cell types. CytoGLMM 
  focuses on just one cell type. Our narrower field of application allows us to 
  define a more specific statistical model with easier to control statistical 
  guarantees. As a result, CytoGLMM finds differential proteins in flow and 
  mass cytometry data while reducing biases arising from marker correlations 
  and safeguarding against false discoveries induced by patient heterogeneity.
License: LGPL-3
URL: https://christofseiler.github.io/CytoGLMM,
        https://github.com/ChristofSeiler/CytoGLMM
BugReports: https://github.com/ChristofSeiler/CytoGLMM/issues
Encoding: UTF-8
Imports: stats, methods, BiocParallel, RColorBrewer, cowplot,
        doParallel, dplyr, factoextra, flexmix, ggplot2, magrittr,
        mbest, pheatmap, stringr, strucchange, tibble, ggrepel, MASS,
        logging, Matrix, tidyr, caret, rlang, grDevices
Suggests: knitr, rmarkdown, testthat, BiocStyle
VignetteBuilder: knitr
RoxygenNote: 7.3.2
biocViews: FlowCytometry, Proteomics, SingleCell, CellBasedAssays,
        CellBiology, ImmunoOncology, Regression, StatisticalMethod,
        Software
git_url: https://git.bioconductor.org/packages/CytoGLMM
git_branch: RELEASE_3_22
git_last_commit: e50528b
git_last_commit_date: 2025-10-29
Repository: Bioconductor 3.22
Date/Publication: 2025-10-29
NeedsCompilation: no
Packaged: 2025-10-30 03:27:02 UTC; biocbuild
Author: Christof Seiler [aut, cre] (ORCID:
    <https://orcid.org/0000-0001-8802-3642>)
Maintainer: Christof Seiler <christof.seiler@maastrichtuniversity.nl>
