lefser

This is the development version of lefser; for the stable release version, see lefser.

R implementation of the LEfSE method for microbiome biomarker discovery


Bioconductor version: Development (3.21)

lefser is the R implementation of the popular microbiome biomarker discovery too, LEfSe. It uses the Kruskal-Wallis test, Wilcoxon-Rank Sum test, and Linear Discriminant Analysis to find biomarkers from two-level classes (and optional sub-classes).

Author: Sehyun Oh [cre, ctb] (ORCID: ), Asya Khleborodova [aut], Samuel Gamboa-Tuz [ctb], Marcel Ramos [ctb] (ORCID: ), Ludwig Geistlinger [ctb] (ORCID: ), Levi Waldron [ctb] (ORCID: )

Maintainer: Sehyun Oh <shbrief at gmail.com>

Citation (from within R, enter citation("lefser")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("lefser")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("lefser")
Quickstart HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Classification, DifferentialExpression, Microbiome, Sequencing, Software, StatisticalMethod
Version 1.17.2
In Bioconductor since BioC 3.12 (R-4.0) (4 years)
License Artistic-2.0
Depends SummarizedExperiment, R (>= 4.0.0)
Imports coin, MASS, ggplot2, S4Vectors, stats, methods, utils, dplyr, testthat, tibble, tidyr, forcats, stringr, ggtree
System Requirements
URL https://github.com/waldronlab/lefser
Bug Reports https://github.com/waldronlab/lefser/issues
See More
Suggests knitr, rmarkdown, curatedMetagenomicData, BiocStyle, phyloseq, pkgdown, covr, withr
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package lefser_1.17.2.tar.gz
Windows Binary (x86_64) lefser_1.17.2.zip
macOS Binary (x86_64) lefser_1.17.2.tgz
macOS Binary (arm64) lefser_1.17.2.tgz
Source Repository git clone https://git.bioconductor.org/packages/lefser
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/lefser
Bioc Package Browser https://code.bioconductor.org/browse/lefser/
Package Short Url https://bioconductor.org/packages/lefser/
Package Downloads Report Download Stats